Our lab investigates the cellular and molecular mechanisms that regulate and coordinate individual hematopoietic stem and progenitor cells during blood and immune cell production. By leveraging cellular heterogeneity, we aim to uncover the quantitative principles that govern hematopoiesis across molecular, cellular, tissue, and organismal levels. Our research seeks to identify critical cell fate transitions and key regulatory genes to improve clinical diagnosis and treatment of hematopoietic diseases.