Year: 2016

In a recent issue of Nature, Philipp S. Hoppe and colleagues present their work on how blood-forming cells, called hematopoietic progenitors, commit to becoming particular blood cell types. Previously, scientists thought that these choices were determined by random changes in the levels of gene regulatory proteins called transcription factors that are linked to programming different…Continue Reading What I’m reading: Rong Lu offers top pick

In an interview with Cell Stem Cell, Drs. Rong Lu, Alvaro Rada-Iglesias, and Jennifer Phillips-Cremins share a behind-the-scenes look at what it took for them to set up their labs and eventually publish their group’s first paper. They share advice, surprises, and frustrations they faced along the way. To read the full article, visit cell.com/cell-stem-cell/fulltext/S1934-5909%2816%2930417-9….Continue Reading Rong Lu tells Cell Stem Cell about the “Path to My Lab’s First Paper”

Few researchers have studied how hematopoietic stem cells respond to infection—even though these are the stem cells that give rise to the full battery of specialized immune cells, such as T cells and B cells. Adnan Chowdhury is venturing into this uncharted territory as the winner of the Hearst Fellowship, which will launch his early…Continue Reading Hearst Fellow Adnan Chowdhury studies how stem cells respond to infection

Congratulations!…Continue Reading Lisa received the ASH Abstract Achievement Award and will give a talk at the ASH meeting

Congratulations!…Continue Reading Du received the first prize of the top poster award at the ISEH meeting

In a recent issue of Nature, Fan Zhou, Bing Liu and colleagues present their work on tracing the developmental origin of blood stem cells, also known as hematopoietic stem cells (HSCs), in mice. Interestingly, grafts of single HSC precursor cells from 11-day-old mouse embryos showed quite different capacities to repopulate the blood. Analysis of gene…Continue Reading What I’m Reading: Rong Lu offers a top pick

Congratulations!…Continue Reading Humberto received an F31 award from NCI

Researchers harness the power of genome editing to track cell lineages throughout zebrafish development. To read more, visit News from The Scientist, and News from Bio Techniques….Continue Reading Rong Commented on Editing Genomes to Record Cellular Histories

Casey Brewer, Ph.D., and colleagues in the laboratory of Rong Lu, Ph.D., discovered that transplantation dose affects the behavior of the blood-forming stem cells in bone marrow hematopoietic stem cells (HSCs). To read more, visit Gen news…Continue Reading Bone Marrow Transplant Success Depends on the Dose

Unlike aspirin, bone marrow doesn’t come with a neatly printed label with dosage instructions. However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow might affect patients undergoing this risky procedure, frequently used to treat cancer and blood diseases. In the study, USC Stem Cell researcher Casey…Continue Reading Dose of transplanted blood-forming stem cells affects their behavior