Rong Lu and Caltech’s Michael Elowitz receive Broad Innovation Award

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MEMOIR
These stem cells contain an engineered genetic system called MEMOIR that allows them to record information about their lineage relationships—including the “parent” and “grandparent” cells from which they descended. This information can then be read out by imaging the cells with specialized microscopes. (Image by Grace Chow/Elowitz Lab)

The Broad Innovation Award is bringing together Rong Lu and Caltech synthetic biologist Michael Elowitz. Their team will study the spatial organization of blood-forming stem and progenitor cells, also called hematopoietic stem and progenitor cells (HSPCs), which reside in the bone marrow. By pinpointing the locations of specific HSPCs, the scientists may find clues to explain why certain HSPCs are so dominant—replenishing the majority of the body’s blood and immune cells after a disruption such as a bone marrow transplantation.

To read more, visit https://stemcell.keck.usc.edu/the-broad-foundation-brings-together-stem-cell-scientists-engineers-and-physicians-at-usc-and-beyond/